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In 1973, Dr. Mutulu Shakur, along with fellow Black Panthers and the Young Lords, combined community health with radical politics to create the first acupuncture detoxification program in America. This form of radical harm reduction was a revolutionary act toward the government programs that transfixed the lives of black and brown communities throughout the South Bronx. Dope is...。A small town infestation of crawling alien foreheads that begin attaching to people and taking them over collides with a scientist's experiments to extract foreheadazine and things go horribly horribly wrong.。1993年，粗鲁张扬的男人约瑟夫·杜森特（乔什·布洛林 Josh Brolin 饰）在深夜遭人绑架。当他醒来时，发现身处一个完全封闭的房间。每天有人按时送来一成不变的饺子，却没人告诉他为什么将其囚禁在这里。他愤怒、沮丧、绝望、哀伤，通过房间里的电视机，得知前妻堂娜·霍桑被人残忍杀害、年仅三岁的女儿米娅被人收养的消息，而自己则背负了杀人犯的罪名。万念俱灰的约瑟夫求死不能，为了女儿他锻炼身体，试图从牢笼中逃脱。漫长的二十年过去，体格健硕的约瑟夫又意外地被人释放。他求助于好朋友恰吉（迈克尔·因佩里奥利 Michael Imperioli 饰），并得到了美丽女孩玛丽的帮助（伊丽莎白·奥尔森 Elizabeth Olsen 饰）。 约瑟夫靠着仅有的线索追查自己被囚禁的原因，而他也终于逼近那个可怕的真相……。